| Gene: | WFS1 |
| mRNA Accession: | AF084481 |
| Mutation: | WFS1.txt |
| Chromosome: | chr 4 |
| Gene: | WFS1 |
| mRNA Accession: | AF084481 |
| Mutation: | WFS1.txt |
| Chromosome: | chr 4 |
| Mutation Submitted | Mutation Instruction | Genomic Coordinate | Position Relative to Natural Site | Closest Natural Site | Initial(Ri) | Final(Ri) | Δ Ri | Fold change | % Binding (Final/Initial) | Initial(Z) | Final(z) | Δ Z |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| c.631G>A Sequence Walker  |
g6285821a | 6285822 | 0 | 6285822 | 5.9 | 2.8 | -3.1 | -8.3 | 12.0 | -0.6 | -1.6 | -0.9 |
| c.1620_1622delGTG Sequence Walker |
d6295869,6295871 | 6295869 | 759 | 6295110 | 4.8 | -13.3 | -18.1 | -27.2 | NA | -1.0 | -6.5 | -5.5 |
| c.1620_1622delGTG Sequence Walker |
d6295869,6295871 | 6295871 | 761 | 6295110 | 3.6 | -23.6 | -27.2 | -12.3 | NA | -1.3 | -9.6 | -8.3 |
| c.1816G>C Sequence Walker |
g6296065c | 6296063 | 953 | 6295110 | 1.3 | -3.1 | -4.4 | -2.4 | NA | -2.0 | -3.4 | -1.3 |
| c.2006A>G Sequence Walker |
a6296255g | 6296253 | 1143 | 6295110 | 1.6 | 1.2 | -0.4 | -1.3 | 75.7 | -1.9 | -2.1 | -0.1 |
| c.2006A>G Sequence Walker |
a6296255g | 6296258 | 1148 | 6295110 | 5.0 | 4.0 | -1.0 | -2.0 | 49.9 | -0.9 | -1.2 | -0.3 |
| c.2100G>T Sequence Walker |
g6296349t | 6296346 | 1236 | 6295110 | 0.6 | 0.0 | -0.5 | -1.4 | 69.3 | -2.3 | -2.4 | -0.2 |
| c.2122C>T Sequence Walker |
c6296371t | 6296374 | 1264 | 6295110 | 2.4 | 0.8 | -1.6 | -3.0 | 32.9 | -1.7 | -2.2 | -0.5 |
| c.2206G>A Sequence Walker |
g6296455a | 6296456 | -1264 | 6297720 | 1.2 | -1.8 | -3.1 | -2.4 | NA | -2.1 | -3.0 | -0.9 |
| c.2338G>C Sequence Walker |
g6296587c | 6296584 | -1136 | 6297720 | 2.1 | 1.6 | -0.5 | -1.4 | 70.6 | -1.8 | -1.9 | -0.2 |
| c.1096C>T Sequence Walker |
c6295345t | 6295339 | 229 | 6295110 | 3.5 | 3.2 | -0.3 | -1.2 | 80.2 | -1.4 | -1.5 | -0.1 |
| c.1380_1388del9 Sequence Walker |
d6295629,6295637 | 6295636 | 526 | 6295110 | 1.8 | -15.9 | -17.7 | -3.5 | NA | -1.9 | -7.3 | -5.4 |
| c.1558C>T Sequence Walker |
c6295807t | 6295810 | 700 | 6295110 | 1.3 | -0.3 | -1.6 | -2.5 | NA | -2.0 | -2.5 | -0.5 |
| c.1611_1624del14 Sequence Walker |
d6295860,6295873 | 6295866 | 756 | 6295110 | 0.8 | -16.7 | -17.5 | -1.7 | NA | -2.2 | -7.5 | -5.3 |
| c.1611_1624del14 Sequence Walker |
d6295860,6295873 | 6295869 | 759 | 6295110 | 4.8 | -14.9 | -19.6 | -27.2 | NA | -1.0 | -7.0 | -6.0 |
| c.1611_1624del14 Sequence Walker |
d6295860,6295873 | 6295871 | 761 | 6295110 | 3.6 | -0.9 | -4.5 | -12.3 | NA | -1.3 | -2.7 | -1.4 |
| c.2002C>T Sequence Walker |
c6296251t | 6296253 | 1143 | 6295110 | 1.6 | 1.5 | -0.1 | -1.1 | 93.5 | -1.9 | -2.0 | -0.0 |
| IVS4+1G>A Sequence Walker |
g6283586a | 6283586 | 0 | 6283586 | 8.4 | -4.4 | -12.8 | -336.3 | NA | 0.1 | -3.8 | -3.9 |