| Gene: | WFS1 |
| mRNA Accession: | AF084481 |
| Mutation: | WFS1.txt |
| Chromosome: | chr 4 |
| Gene: | WFS1 |
| mRNA Accession: | AF084481 |
| Mutation: | WFS1.txt |
| Chromosome: | chr 4 |
| Mutation Submitted | Mutation Instruction | Genomic Coordinate | Position Relative to Natural Site | Closest Natural Site | Initial(Ri) | Final(Ri) | Δ Ri | Fold change | % Binding (Final/Initial) | Initial(Z) | Final(z) | Δ Z |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| c.887T>G Sequence Walker |
t6295136g | 6295136 | 26 | 6295110 | -7.5 | 1.2 | 8.7 | 2.4 | 235.3 | -3.6 | -1.7 | 1.9 |
| c.1243_1245delGTC Sequence Walker  |
d6295492,6295494 | 6295496 | 386 | 6295110 | 2.6 | 4.3 | 1.7 | 3.2 | 324.8 | -1.4 | -1.0 | 0.4 |
| c.1243_1245delGTC Sequence Walker |
d6295492,6295494 | 6295509 | 399 | 6295110 | 0.9 | 1.4 | 0.5 | 1.4 | 142.3 | -1.7 | -1.6 | 0.1 |
| c.1243_1245delGTC Sequence Walker |
d6295492,6295494 | 6295511 | 401 | 6295110 | 4.6 | 4.8 | 0.2 | 1.2 | 115.4 | -0.9 | -0.9 | 0.0 |
| c.1243_1245delGTC Sequence Walker |
d6295492,6295494 | 6295513 | 403 | 6295110 | 4.0 | 5.1 | 1.1 | 2.1 | 214.4 | -1.1 | -0.8 | 0.2 |
| c.1243_1245delGTC Sequence Walker |
d6295492,6295494 | 6295517 | 407 | 6295110 | 9.2 | 10.1 | 0.9 | 1.9 | 185.5 | 0.1 | 0.3 | 0.2 |
| c.1309G>C Sequence Walker |
g6295558c | 6295577 | 467 | 6295110 | 4.5 | 5.3 | 0.8 | 1.7 | 172.4 | -1.0 | -0.8 | 0.2 |
| c.1309G>C Sequence Walker |
g6295558c | 6295570 | 460 | 6295110 | -0.8 | 0.8 | 1.6 | 1.7 | 168.7 | -2.1 | -1.8 | 0.3 |
| c.1514G>A Sequence Walker |
g6295763a | 6295782 | 672 | 6295110 | -0.1 | 0.1 | 0.2 | 1.0 | 104.8 | -2.0 | -1.9 | 0.0 |
| c.1816G>C Sequence Walker |
g6296065c | 6296084 | 974 | 6295110 | -0.7 | 0.1 | 0.8 | 1.1 | 107.0 | -2.1 | -1.9 | 0.2 |
| c.2051C>T Sequence Walker |
c6296300t | 6296321 | 1211 | 6295110 | 3.1 | 3.1 | 0.1 | 1.0 | 104.0 | -1.3 | -1.3 | 0.0 |
| c.2068T>C Sequence Walker |
t6296317c | 6296339 | 1229 | 6295110 | 0.6 | 0.6 | 0.1 | 1.0 | 103.5 | -1.8 | -1.8 | 0.0 |
| c.2084G>T Sequence Walker |
g6296333t | 6296331 | 1221 | 6295110 | 1.6 | 2.1 | 0.5 | 1.4 | 142.8 | -1.6 | -1.5 | 0.1 |
| c.2084G>T Sequence Walker |
g6296333t | 6296339 | 1229 | 6295110 | 0.6 | 2.8 | 2.2 | 4.6 | 459.4 | -1.8 | -1.3 | 0.5 |
| c.2171C>T Sequence Walker |
c6296420t | 6296431 | -1289 | 6297720 | 2.0 | 2.5 | 0.5 | 1.5 | 146.3 | -1.5 | -1.4 | 0.1 |
| c.2171C>T Sequence Walker |
c6296420t | 6296432 | -1288 | 6297720 | -0.3 | 0.1 | 0.4 | 1.1 | 108.4 | -2.0 | -1.9 | 0.1 |
| c.2206G>A Sequence Walker |
g6296455a | 6296477 | -1243 | 6297720 | 3.4 | 3.8 | 0.4 | 1.4 | 135.5 | -1.2 | -1.1 | 0.1 |
| c.2206G>A Sequence Walker |
g6296455a | 6296456 | -1264 | 6297720 | -4.0 | 4.2 | 8.2 | 18.1 | 1812.6 | -2.8 | -1.0 | 1.8 |
| c.2338G>C Sequence Walker |
g6296587c | 6296603 | -1117 | 6297720 | 1.1 | 2.3 | 1.2 | 2.4 | 236.6 | -1.7 | -1.4 | 0.3 |
| c.2338G>C Sequence Walker |
g6296587c | 6296600 | -1120 | 6297720 | -0.0 | 1.3 | 1.3 | 2.4 | 243.0 | -1.9 | -1.7 | 0.3 |
| c.2452C>T Sequence Walker |
c6296701t | 6296706 | -1014 | 6297720 | 2.4 | 2.6 | 0.2 | 1.1 | 114.0 | -1.4 | -1.4 | 0.0 |
| c.2654C>T Sequence Walker |
c6296903t | 6296910 | -810 | 6297720 | 6.1 | 6.1 | 0.0 | 1.0 | 102.7 | -0.6 | -0.6 | 0.0 |
| c.2654C>T Sequence Walker |
c6296903t | 6296913 | -807 | 6297720 | 6.2 | 6.9 | 0.7 | 1.6 | 160.4 | -0.6 | -0.4 | 0.1 |
| c.2654C>T Sequence Walker |
c6296903t | 6296914 | -806 | 6297720 | 3.0 | 3.6 | 0.5 | 1.5 | 146.3 | -1.3 | -1.2 | 0.1 |
| c.2654C>T Sequence Walker |
c6296903t | 6296917 | -803 | 6297720 | 0.4 | 0.8 | 0.4 | 1.3 | 130.0 | -1.9 | -1.8 | 0.1 |
| c.2654C>T Sequence Walker |
c6296903t | 6296923 | -797 | 6297720 | 1.2 | 1.4 | 0.2 | 1.1 | 111.8 | -1.7 | -1.6 | 0.0 |
| c.2654C>T Sequence Walker |
c6296903t | 6296916 | -804 | 6297720 | -0.2 | 0.2 | 0.4 | 1.2 | 117.8 | -2.0 | -1.9 | 0.1 |
| c.1038_1039insC Sequence Walker |
i6295287,6295288c | 6295302 | 192 | 6295110 | 0.5 | 0.5 | 0.0 | 1.0 | 102.7 | -1.8 | -1.8 | 0.0 |
| c.1433G>A Sequence Walker |
g6295682a | 6295683 | 573 | 6295110 | -7.8 | 0.3 | 8.2 | 1.2 | 124.3 | -3.7 | -1.9 | 1.8 |
| c.1433G>A Sequence Walker |
g6295682a | 6295707 | 597 | 6295110 | -0.1 | 0.4 | 0.6 | 1.3 | 134.5 | -2.0 | -1.8 | 0.1 |
| c.1523_1524delAT Sequence Walker |
d6295772,6295773 | 6295782 | 672 | 6295110 | -0.1 | 0.4 | 0.6 | 1.3 | 134.8 | -2.0 | -1.8 | 0.1 |
| c.1525_1537del13 Sequence Walker |
d6295774,6295786 | 6295807 | 697 | 6295110 | 1.8 | 2.2 | 0.4 | 1.3 | 130.9 | -1.5 | -1.5 | 0.1 |
| c.1549delC Sequence Walker |
d6295798,6295798 | 6295802 | 692 | 6295110 | 6.1 | 6.4 | 0.3 | 1.2 | 124.5 | -0.6 | -0.5 | 0.1 |
| c.1549delC Sequence Walker |
d6295798,6295798 | 6295807 | 697 | 6295110 | 1.8 | 1.9 | 0.1 | 1.1 | 109.6 | -1.5 | -1.5 | 0.0 |
| c.1602C>G Sequence Walker |
c6295851g | 6295851 | 741 | 6295110 | -1.5 | 5.8 | 7.3 | 55.1 | 5513.1 | -2.3 | -0.7 | 1.6 |
| c.1999C>T Sequence Walker |
c6296248t | 6296253 | 1143 | 6295110 | 0.4 | 0.6 | 0.2 | 1.1 | 114.0 | -1.9 | -1.8 | 0.0 |
| c.2254G>T Sequence Walker |
g6296503t | 6296523 | -1197 | 6297720 | -0.4 | 0.8 | 1.2 | 1.8 | 177.2 | -2.0 | -1.8 | 0.3 |
| c.2433delA Sequence Walker |
d6296682,6296682 | 6296706 | -1014 | 6297720 | 2.4 | 2.8 | 0.4 | 1.3 | 130.5 | -1.4 | -1.3 | 0.1 |
| c.2504_2505insC Sequence Walker |
i6296753,6296754c | 6296778 | -942 | 6297720 | 2.1 | 3.0 | 0.9 | 1.9 | 188.4 | -1.5 | -1.3 | 0.2 |
| c.2638_2643del6 Sequence Walker |
d6296887,6296892 | 6296910 | 1800 | 6295110 | 6.1 | 6.6 | 0.5 | 1.4 | 141.7 | -0.6 | -0.5 | 0.1 |
| c.2638_2643del6 Sequence Walker |
d6296887,6296892 | 6296913 | 1803 | 6295110 | 6.2 | 6.5 | 0.3 | 1.3 | 126.8 | -0.6 | -0.5 | 0.1 |
| c.2648_2651delTCTT Sequence Walker |
d6296897,6296900 | 6296917 | 1807 | 6295110 | 0.4 | 0.4 | 0.0 | 1.0 | 101.9 | -1.9 | -1.8 | 0.0 |