Gene: NF1
mRNA Accession: M82814
Mutation:NF1.txt
Chromosome: chr 17

Sequence Walker  


Information Increased
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1465-1466insC
Sequence Walker   		i29389901,29389902c 29389918 -1448 29391366 0.1 0.2 0.1 1.1 105.1 -1.9 -1.9 0.0
1465-1466insC
Sequence Walker   		i29389901,29389902c 29389903 -1463 29391366 -0.0 2.9 2.9 7.3 729.4 -1.9 -1.3 0.6
1570G>T
Sequence Walker   		g29395963t 29395975 55 29395920 -1.3 0.7 2.0 1.6 162.0 -2.2 -1.8 0.4
1607C>A
Sequence Walker   		c29396000a 29395998 -37 29396035 2.0 2.4 0.5 1.4 138.3 -1.5 -1.4 0.1
2033-2034insC
Sequence Walker   		i29401317,29401318c 29401325 -2025 29403350 5.5 6.3 0.8 1.7 171.4 -0.7 -0.6 0.2
2033-2034insC
Sequence Walker   		i29401317,29401318c 29401334 -2016 29403350 9.8 9.9 0.0 1.0 101.2 0.2 0.2 0.0
2540T>C
Sequence Walker   		t29406071c 29406073 133 29405940 1.6 3.3 1.7 3.2 315.6 -1.6 -1.2 0.4
2540T>C
Sequence Walker   		t29406071c 29406074 134 29405940 0.9 1.2 0.3 1.2 121.4 -1.7 -1.7 0.1
2540T>C
Sequence Walker   		t29406071c 29406093 153 29405940 2.1 2.1 0.0 1.0 103.5 -1.5 -1.5 0.0
2875C>T
Sequence Walker   		c29406775t 29406784 34 29406750 2.0 2.5 0.6 1.5 149.8 -1.5 -1.4 0.1
2887C>T
Sequence Walker   		c29406787t 29403792 -2958 29406750 -0.4 0.5 0.9 1.4 136.9 -2.0 -1.8 0.2
3826C>T
Sequence Walker   		c29412644t 29412654 -35 29412689 2.1 2.8 0.7 1.6 160.4 -1.5 -1.3 0.1
4084C>T
Sequence Walker   		c29426009t 29426013 -23 29426036 3.6 4.2 0.6 1.5 154.9 -1.1 -1.0 0.1
888del174
Sequence Walker   		d29359408,29359581 29359734 152 29359582 0.0 4.5 4.5 22.7 2271.6 0.0 -1.0 -1.0
IVS26-2A>T
Sequence Walker   		a29409916t 29409923 6 29409917 2.3 4.3 2.0 3.9 391.8 -1.4 -1.0 0.4
IVS26-2A>T
Sequence Walker   		a29409916t 29409934 17 29409917 -0.6 0.5 1.1 1.4 142.5 -2.1 -1.8 0.2