Gene: NF1
mRNA Accession: M82814
Mutation:NF1.txt
Chromosome: chr 17

Sequence Walker  


No Change of Information Content
Mutation SubmittedMutation InstructionGenomic CoordinatePosition Relative
to Natural Site		Closest
Natural Site		Initial(Ri)Final(Ri)Δ RiFold change% Binding (Final/Initial)Initial(Z)Final(z)Δ Z
1275G>A
Sequence Walker   		g29383170a 29383155 0 29383155 11.1 11.1 0.0 1.0 100 0.5 0.5 0.0
1275G>A
Sequence Walker   		g29383170a 29383159 4 29383155 1.0 1.0 0.0 1.0 100 -1.7 -1.7 0.0
1275G>A
Sequence Walker   		g29383170a 29383162 7 29383155 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
1275G>A
Sequence Walker   		g29383170a 29383164 9 29383155 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
1465-1466insC
Sequence Walker   		i29389901,29389902c 29389950 -1416 29391366 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
1466A>G
Sequence Walker   		a29391440g 29391481 -21 29391502 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
1570G>T
Sequence Walker   		g29395963t 29395998 78 29395920 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
1570G>T
Sequence Walker   		g29395963t 29396011 91 29395920 1.8 1.8 0.0 1.0 100 -1.5 -1.5 0.0
2033-2034insC
Sequence Walker   		i29401317,29401318c 29401361 -1989 29403350 4.3 4.3 0.0 1.0 100 -1.0 -1.0 0.0
2033-2034insC
Sequence Walker   		i29401317,29401318c 29401367 -1983 29403350 1.6 1.6 0.0 1.0 100 -1.6 -1.6 0.0
2540T>C
Sequence Walker   		t29406071c 29406122 182 29405940 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
278G>A
Sequence Walker   		g29335999a 29335970 -40 29336010 5.1 5.1 0.0 1.0 100 -0.8 -0.8 0.0
2875C>T
Sequence Walker   		c29406775t 29406750 0 29406750 12.8 12.8 0.0 1.0 100 0.9 0.9 0.0
2875C>T
Sequence Walker   		c29406775t 29406751 1 29406750 0.3 0.3 0.0 1.0 100 -1.9 -1.9 0.0
2875C>T
Sequence Walker   		c29406775t 29406759 9 29406750 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
2875C>T
Sequence Walker   		c29406775t 29406763 13 29406750 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
2887C>T
Sequence Walker   		c29406787t 29406759 9 29406750 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
2887C>T
Sequence Walker   		c29406787t 29406763 13 29406750 1.1 1.1 0.0 1.0 100 -1.7 -1.7 0.0
2887C>T
Sequence Walker   		c29406787t 29406784 34 29406750 2.0 2.0 0.0 1.0 100 -1.5 -1.5 0.0
3274del40
Sequence Walker   		d29409026,29409065 29409106 0 29409106 0.6 0.6 0.0 1.0 100 -1.8 -1.8 0.0
3274del40
Sequence Walker   		d29409026,29409065 29409116 10 29409106 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
3277G>A
Sequence Walker   		g29409068a 29409046 -60 29409106 1.0 1.0 0.0 1.0 100 -1.7 -1.7 0.0
3277G>A
Sequence Walker   		g29409068a 29409049 -57 29409106 9.8 9.8 0.0 1.0 100 0.2 0.2 0.0
3277G>A
Sequence Walker   		g29409068a 29409056 -50 29409106 3.4 3.4 0.0 1.0 100 -1.2 -1.2 0.0
3277G>A
Sequence Walker   		g29409068a 29409106 0 29409106 0.6 0.6 0.0 1.0 100 -1.8 -1.8 0.0
3277G>A
Sequence Walker   		g29409068a 29409116 10 29409106 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
3367G>T
Sequence Walker   		g29409668t 29409654 39 29409615 2.5 2.5 0.0 1.0 100 -1.4 -1.4 0.0
3520C>T
Sequence Walker   		c29409941t 29409912 -5 29409917 0.0 0.0 0.0 1.0 100 -1.9 -1.9 0.0
3520C>T
Sequence Walker   		c29409941t 29409917 0 29409917 5.5 5.5 0.0 1.0 100 -0.7 -0.7 0.0
3520C>T
Sequence Walker   		c29409941t 29409923 6 29409917 2.3 2.3 0.0 1.0 100 -1.4 -1.4 0.0
3826C>T
Sequence Walker   		c29412644t 29412688 -1 29412689 2.7 2.7 0.0 1.0 100 -1.3 -1.3 0.0
4084C>T
Sequence Walker   		c29426009t 29425980 -56 29426036 3.1 3.1 0.0 1.0 100 -1.3 -1.3 0.0
4084C>T
Sequence Walker   		c29426009t 29425991 -45 29426036 8.6 8.6 0.0 1.0 100 -0.1 -0.1 0.0
4084C>T
Sequence Walker   		c29426009t 29426005 -31 29426036 0.4 0.4 0.0 1.0 100 -1.8 -1.8 0.0
4084C>T
Sequence Walker   		c29426009t 29426035 -1 29426036 4.5 4.5 0.0 1.0 100 -0.9 -0.9 0.0
4084C>T
Sequence Walker   		c29426009t 29426047 11 29426036 3.5 3.5 0.0 1.0 100 -1.2 -1.2 0.0
4537C>T
Sequence Walker   		c29438649t 29438626 0 29438626 4.9 4.9 0.0 1.0 100 -0.9 -0.9 0.0
4537C>T
Sequence Walker   		c29438649t 29438697 71 29438626 7.6 7.6 0.0 1.0 100 -0.3 -0.3 0.0
4537C>T
Sequence Walker   		c29438649t 29438699 73 29438626 0.3 0.3 0.0 1.0 100 -1.9 -1.9 0.0
560G>A
Sequence Walker   		g29346887a 29346859 -55 29346914 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
603-604insT
Sequence Walker   		i29357734,29357735t 29357774 -563 29358337 1.4 1.4 0.0 1.0 100 -1.6 -1.6 0.0
910C>T
Sequence Walker   		c29377359t 29377337 0 29377337 5.7 5.7 0.0 1.0 100 -0.7 -0.7 0.0
910C>T
Sequence Walker   		c29377359t 29377354 17 29377337 0.6 0.6 0.0 1.0 100 -1.8 -1.8 0.0
987-988insA
Sequence Walker   		i29376350,29376351a 29376326 -1011 29377337 1.3 1.3 0.0 1.0 100 -1.7 -1.7 0.0
987-988insA
Sequence Walker   		i29376350,29376351a 29376332 -1005 29377337 2.2 2.2 0.0 1.0 100 -1.5 -1.5 0.0
987-988insA
Sequence Walker   		i29376350,29376351a 29376397 -940 29377337 2.5 2.5 0.0 1.0 100 -1.4 -1.4 0.0
IVS16+3del6
Sequence Walker   		d29400486,29400491 29400458 -26 29400484 1.2 1.2 0.0 1.0 100 -1.7 -1.7 0.0
IVS16-6del4
Sequence Walker   		d29400354,29400357 29400386 27 29400359 3.8 3.8 0.0 1.0 100 -1.1 -1.1 0.0
IVS16-6del4
Sequence Walker   		d29400354,29400357 29400387 28 29400359 3.5 3.5 0.0 1.0 100 -1.2 -1.2 0.0
IVS26-2A>T
Sequence Walker   		a29409916t 29409912 -5 29409917 0.0 0.0 0.0 1.0 100 -1.9 -1.9 0.0