Molecular Cytogenetics Resources

Over the past 40 years, cytogenetics has become the gold standard for chromosome analysis in clinical and research laboratories.  Giemsa and other types of chromosome banding techniques are used to definitively diagnose inherited and acquired genetic disorders. Molecular cytogenetics, a relatively recent development, permits detection of chromosome abnormalities at single or multigene resolution.

• Publications from the Laboratories of Human Molecular Genetics and Genomic Disorders here.

• Our published FISH protocol: J. Knoll and P. Lichter, Unit 4.3, Current Protocols in Human Genetics, Wiley NY

• Integrated Automated Molecular Cytogenetic System here

• Lecture: Introduction to Cytogenetics here.

• Lecture: Telomeres and disease here.

• Lecture: Genetic chimerism in humans here.

Protocols in Molecular Cytogenetics here.

Recent review on Molecular Cytogenetics applications here.

Cytogenetics Resources Links page at KUMC (Many sites, mostly educational) here.

Multiple Congenital Anomaly/Mental Retardation Syndrome Database at National Library of Medicine here.

Online Mendelian Inheritance of Man here.